Androgenetic alopecia (male and woman pattern balding) is by far the most common cause of hair loss amongst men and a serious trouble for many women. There are three essential components which are responsible for both female and male balding:

1. A genetic predisposition for balding to occur.

2. Excessive presence of male hormones.

3. Aging – adequate time for the first two factors to occur.

Together men and women produce male hormones that have a useful role to play inside both sexes; but the detail that androgens occur in much higher concentrations inside men explains why male pattern baldness is extra common than the female balding.

DHT the root cause of hair loss
It is metabolism of male hormones (androgen/testosterone) which is important cause of hair loss and male and woman pattern balding together in men and women.

The metabolism of androgen involves an enzyme called 5 alpha reductase which combines using the hormone (testosterone) and converts it to DHT (Dihydro-testosterone). DHT is a expected metabolite of our body.

The cause of male and female pattern balding
Any individuals, both men and women, are genetically pre-disposed to produce more DHT than the usual individuals. It is this accumulation of DHT and its effect on the cells inside the hair follicle and root which is one of the basic causes of male and lady pattern balding.

When DHT gets into the hair follicle and root, especially a region called the dermal papilla, it changes the cell’ activity and prevents required proteins, vitamins and minerals from providing nourishment considered necessary to sustain life inside the hairs of those follicles. Consequently, hair follicles are reproduced at a much slower rate. This shortens their growing stage (anagen phase) and or lengthens their resting stage (telogen phase) of the follicle. DHT also causes hair follicle to shrink and pay for progressively smaller and finer. This process is known since miniaturization and causes the hair to ultimately fall. DHT induced androgenetic aloepcia is responsible for 95% of all hair loss.

Blocking the synthesis of DHT at the molecular level forms the basis for the heal of MPHL (male pattern hair loss) and FPHL (female pattern hair loss). There are a variety of usual DHT blockers and various drugs which are used for medical hair restoration.

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